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    Freshman Organic Chemistry II (CHEM 125B)

    Isoprenoid or terpene natural products, that seem to be made from isoprene (2-methylbutadiene), are formed by oligomerization of electrophilic isopentenyl pyrophosphate (IPP). Latex, the polymer of IPP, became commercially important when Charles Goodyear, a New Haven native, discovered how to vulcanize rubber. Statistical mechanics explains such curious properties of rubber as contraction upon heating when tightly stretched. Specific chemical treatment confers useful properties on a wide variety of polymers, including hair, synthetic rubber, and plastics. The structure of copolymers demonstrates non-Hammond behavior and ionic character in the transition state for free-radical polymerization.

    00:00 – Chapter 1. IPP as the Carbon Electrophile in Isoprenoid Biosynthesis
    13:56 – Chapter 2. Latex, Rubber, and Vulcanization
    20:14 – Chapter 3. Understanding Vulcanization – Polymer Properties and Statistical Mechanics
    35:34 – Chapter 4. Other Polymers and Their Properties
    38:22 – Chapter 5. Synthetic Polymers and Free-Radical Copolymerization

    Complete course materials are available at the Open Yale Courses website: https://oyc.yale.edu

    This course was recorded in Spring 2011.